Genetic risk variants for childhood nephrotic syndrome and corticosteroid response
Rachel Kate Cason, Eileen T Chambers, Tiffany Tu, Megan Chryst-Stangl, Kinsie Huggins, Brandon M Lane, Alejandro Ochoa, Annette M Jackson, Rasheed Gbadegesin
Frontiers in Pediatrics 11:1248733. 2023-10-06
Publications
Limitations of principal components in quantitative genetic association models for human studies
Yiqi Yao, Alejandro Ochoa
eLife 79238. 2023-05-04
Genetic association models are robust to common population kinship estimation biases
Zhuoran Hou, Alejandro Ochoa
Genetics iyad030. 2023-02-27
CLVS1, a candidate gene for steroid sensitive nephrotic syndrome, regulates podocyte oxidative stress and endocytosis
Brandon M Lane, Megan Chryst-Stangl, Guanghong Wu, Mohamed Shalaby, Sherif El Desoky, Claire Middleton, Kinsie Huggins, Amika Sood, Alejandro Ochoa, Andrew F Malone, Ricardo Vancini, Sara Miller, Gentzon Hall, So Young Kim, David Howell, Jameela A Kari, Rasheed Gbadegesin
JCI Insight 7(2) e152102. 2021-12-07
HLA Loci and Recurrence of Focal Segmental Glomerulosclerosis In Pediatric Kidney Transplantation
Brian I Shaw, Alejandro Ochoa, Cliburn Chan, Chloe Nobuhara, Rasheed Gbadegesin, Annette M Jackson, Eileen T Chambers
Transplant Direct 7(10) e748. 2021-08-26
Correcting signal biases and detecting regulatory elements in STARR-seq data
Young-Sook Kim, Graham D Johnson, Jungkyun Seo, Alejandro Barrera, Thomas N. Cowart, William H Majoros, Alejandro Ochoa, Andrew S Allen, Timothy E Reddy
Genome Res 31(5) 877-889. 2021-05-01
Estimating FST and kinship for arbitrary population structures
Alejandro Ochoa, John D Storey
PLoS Genet 17(1) e1009241. 2021-01-19
New kinship and FST estimates reveal higher levels of differentiation in the global human population
Alejandro Ochoa, John D Storey
bioRxiv doi:10.1101/653279. 2019-05-30
Domain prediction with probabilistic directional context
Alejandro Ochoa, Mona Singh
Bioinf 33(16) 2471-8. 2017-04-12
FST and kinship for arbitrary population structures I: Generalized definitions
Alejandro Ochoa, John D Storey
bioRxiv doi:10.1101/083915. 2016-10-27
Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite
Simon A Cobbold, Joana M Santos, Alejandro Ochoa, David H Perlman, Manuel Llinás
Sci Rep 2016;6:19722. 2016-01-27
Beyond the E-value: stratified statistics for protein domain prediction
Alejandro Ochoa, John D Storey, Manuel Llinás, Mona Singh
PLoS Comput Biol 11 e1004509. 2015-11-17
Evolution and diversity in human herpes simplex virus genomes
Moriah L Szpara, Derek Gatherer, Alejandro Ochoa, Benjamin Greenbaum, Aidan Dolan, Rory J Bowden, Lynn W Enquist, Matthieu Legendre, Andrew J Davison
J Virol 88:1209-27. 2013-11-13
Using context to improve protein domain identification
Alejandro Ochoa, Manuel Llinás, Mona Singh
BMC Bioinformatics 12:90. 2011-03-31
Computing van der Waals energies in the context of the rotamer approximation
Gevorg Grigoryan, Alejandro Ochoa, Amy E Keating
Proteins 68(4) 863-78. 2007-11-01